25.08 - 30.08.2019  STATUS
Spetses Island, Greece

The objective of the summer school on ‘Epigenomics, Nuclear Receptors and Disease’ (FEBS ALC19-046) at the Island of Spetses in Greece, is to provide a unique meeting opportunity for young scientists (PhD students and postdocs) in the broader fields of epigenomics and nuclear receptor signaling, and in particular to cross-fertilize the fields in order to better understand disease mechanisms. Epigenomics can be described as the integrated study of components and mechanisms that regulate gene expression under physiological and pathophysiological conditions. Nuclear receptors are significant drug targets and todays best-studied signal-responsive transcription factors that in response to environmental and nutritional inputs modulate or even trigger epigenome alterations towards disease.

Renowned lecturers and discussion leaders will introduce the current concepts and methodologies along with key components, including transcription factors, coregulators, chromatin modifications, promoters, enhancers and non-coding RNAs. This is followed by in-depth discussions of mechanisms and alterations underlying metabolic, inflammatory and proliferative diseases as well as ageing.

The course program is designed to actively encourage multiple student activities and networking during workshops, tutorial lunches and dinners, poster sessions and individual discussions every day, thereby stimulating the scientific dialogue and creating a familiar and inspiring atmosphere. All students and lecturers will stay at the Spetses Hotel offering modern meeting facilities, idyllic surroundings, excellent possibilities for recreation and exploration of Greek culture, bars and restaurants.

Applications closing: 6 May 2019

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